In ProxySQL 2.0.4 , libssl was upgrade from 1.1.0h to 1.1.1b . In ProxySQL 2.0.7 , libssl was downgraded back to 1.1.0h . See [bug 2244](https://github.com/sysown/proxysql/issues/2244) . In ProxySQL 2.1.1 , libssl was upgraded to version 1.1.1j In ProxySQL 2.4.0 , libssl was upgraded from version 1.1.1j to 3.0.2 Do not upgrade without extensive testing. See note about `struct bio_st` in MySQL_Data_Stream.cpp .